Dr. Merched received his Ph.D. in Clinical Biochemistry and Human
Molecular Genetics from the University of Nancy, France in 1998, and
spent 5 years as a Post Doc in Molecular and Cellular Biology at Baylor
College of Medicine. In 2003, he was appointed to the faculty at the
Instructor level, and in 2004, he was promoted to Assistant Professor
of Molecular and Cellular Biology at Baylor.
His awards and honors include American Heart Association, French
Ministry of Education, Bayer Pharmaceuticals, French Committee for
Coordination of Research in Atherosclerosis and Cholesterol and
Lipids, Hariri Foundation.
Dr. Merched has authored and co-authored over 50 publications,
invited talks, and conference proceedings. He is currently a member
of the American Heart Association, the International Society of
Atherosclerosis, and the American Society of Gene Therapy.
Dr. Merched's research interests have focused on the basic research
of cardiovascular diseases and atherosclerosis or hardening of the
arteries (*).
A large part of Dr. Merched’s current research effort consist of
understanding genes contributing to the build up of atherosclerotic
lesions. All stages of the pathological process are investigated
including recruitment of inflammatory cells to sites of injury in the
arterial wall, lipid uptake and accumulation, cell death and
proliferation. Success depends on keeping up with the latest cellular
and molecular technical advances, surgical procedures, using and
creating the latest genetically modified animal models.
The practical objective of our research is to understand the genetic
information and the regulation pathways to identify pharmaceutical
targets and to design more efficacious interventions. Our studies are
defining, at the molecular level, novel mechanisms of atherogenesis.
Molecular Genetics from the University of Nancy, France in 1998, and
spent 5 years as a Post Doc in Molecular and Cellular Biology at Baylor
College of Medicine. In 2003, he was appointed to the faculty at the
Instructor level, and in 2004, he was promoted to Assistant Professor
of Molecular and Cellular Biology at Baylor.
His awards and honors include American Heart Association, French
Ministry of Education, Bayer Pharmaceuticals, French Committee for
Coordination of Research in Atherosclerosis and Cholesterol and
Lipids, Hariri Foundation.
Dr. Merched has authored and co-authored over 50 publications,
invited talks, and conference proceedings. He is currently a member
of the American Heart Association, the International Society of
Atherosclerosis, and the American Society of Gene Therapy.
Dr. Merched's research interests have focused on the basic research
of cardiovascular diseases and atherosclerosis or hardening of the
arteries (*).
A large part of Dr. Merched’s current research effort consist of
understanding genes contributing to the build up of atherosclerotic
lesions. All stages of the pathological process are investigated
including recruitment of inflammatory cells to sites of injury in the
arterial wall, lipid uptake and accumulation, cell death and
proliferation. Success depends on keeping up with the latest cellular
and molecular technical advances, surgical procedures, using and
creating the latest genetically modified animal models.
The practical objective of our research is to understand the genetic
information and the regulation pathways to identify pharmaceutical
targets and to design more efficacious interventions. Our studies are
defining, at the molecular level, novel mechanisms of atherogenesis.
| Aksam Merched, Ph.D Assistant Professor Baylor College of Medicine, Molecular & Cellular Biology One Baylor Plaza, BCMM-M609 Room#N503 Houston, TX 77030 USA Send email |
* Atherosclerosis is the process in which deposits of fatty
substances, cholesterol, cellular waste products, calcium
and other substances build up in the inner lining of an
artery. This buildup is called plaque. It usually affects
large and medium-sized arteries. Some hardening of
arteries often occurs when people grow older. Plaques
can grow large enough to significantly reduce the
blood's flow through an artery. But most of the damage
occurs when they become fragile and rupture. Plaques
that rupture cause blood clots to form that can block
blood flow or break off and travel to another part of the
body. If either happens and blocks a blood vessel that
feeds the heart, it causes a heart attack. If it blocks a
blood vessel that feeds the brain, it causes a stroke.
(from American Heart Association click for more details)
substances, cholesterol, cellular waste products, calcium
and other substances build up in the inner lining of an
artery. This buildup is called plaque. It usually affects
large and medium-sized arteries. Some hardening of
arteries often occurs when people grow older. Plaques
can grow large enough to significantly reduce the
blood's flow through an artery. But most of the damage
occurs when they become fragile and rupture. Plaques
that rupture cause blood clots to form that can block
blood flow or break off and travel to another part of the
body. If either happens and blocks a blood vessel that
feeds the heart, it causes a heart attack. If it blocks a
blood vessel that feeds the brain, it causes a stroke.
(from American Heart Association click for more details)
| Dr. Aksam J. Merched's Homepage |
 |  |  |
Aksam Merched's latest discoveries of novel ways to treat
cardiovascular diseases reported in several media outlets and
research institutions:
Baylor College of Medicine Media Center (Houston, Texas)
Canadian Broadcasting Corporation CBC News
British Cardiovascular Society
United Press International
Daily India
Herald Globe
Washington DC News
EurekAlert (American Association for the Advancement of Science
AAAS): release 1, release 2.
BreakThrough Digest, Medical News Today,
Top 100, Bio Medicine
Genetic Engineering & Biotechnology News
and many others (South Asia News, Yahoo India, Science Daily, Senior
Journal, Thaindian News, Med India, Physorg, Med Compare, Huliq
News, Top News, Brightsurf, Lab spaces, Science Centric, News
Guide, e! Science News, Preventive Medicine, Etc...)
Research published at FASEB Journal and Press Room.
Fore more details at: Bterram's links
cardiovascular diseases reported in several media outlets and
research institutions:
Baylor College of Medicine Media Center (Houston, Texas)
Canadian Broadcasting Corporation CBC News
British Cardiovascular Society
United Press International
Daily India
Herald Globe
Washington DC News
EurekAlert (American Association for the Advancement of Science
AAAS): release 1, release 2.
BreakThrough Digest, Medical News Today,
Top 100, Bio Medicine
Genetic Engineering & Biotechnology News
and many others (South Asia News, Yahoo India, Science Daily, Senior
Journal, Thaindian News, Med India, Physorg, Med Compare, Huliq
News, Top News, Brightsurf, Lab spaces, Science Centric, News
Guide, e! Science News, Preventive Medicine, Etc...)
Research published at FASEB Journal and Press Room.
Fore more details at: Bterram's links
| Please visit updated website at: BCM Merched's Site |