Communications presented in scientific meetings and workshops
(China, France, Italy, Germany, Belgium, USA, Canada, Singapor,...).
During the last 2 years:
Merched A. Chairman Session Lipid & Atherosclerosis. BIT's 1st Annual International Congress of Cardiology. December
5-7, 2009 Shanghai, China.
Merched A. Bioactive Lipid Mediators and Resolution of Cardiovascular Inflammation. invited talk. BIT's 1st Annual
International Congress of Cardiology December 5-7, 2009 Shanghai, China.
Merched A.J., Ko K., Gotlinger K.H., Charles N. Serhan C.N., Chan L. Atherosclerosis is a nonresolving form of vascular
inflammation, governed by specific lipid mediators and macrophage responses. Oral. 6eme Congrès Annuel NSFA - June
9-11, 2009, Avignon, France.
(China, France, Italy, Germany, Belgium, USA, Canada, Singapor,...).
During the last 2 years:
Merched A. Chairman Session Lipid & Atherosclerosis. BIT's 1st Annual International Congress of Cardiology. December
5-7, 2009 Shanghai, China.
Merched A. Bioactive Lipid Mediators and Resolution of Cardiovascular Inflammation. invited talk. BIT's 1st Annual
International Congress of Cardiology December 5-7, 2009 Shanghai, China.
Merched A.J., Ko K., Gotlinger K.H., Charles N. Serhan C.N., Chan L. Atherosclerosis is a nonresolving form of vascular
inflammation, governed by specific lipid mediators and macrophage responses. Oral. 6eme Congrès Annuel NSFA - June
9-11, 2009, Avignon, France.
in pictures....
| Council on Basic Cardiovascular Sciences dinner and business meeting Nov 2005 |
| Talk at AHA meeting Dallas 2005 |
| NSFA 2005, Biarritz |
| Basque Barbecue NSFA 2005, Biarritz |
| AHA meeting New Orleans, Louisiana, 2004 |
| During NSFA meeting (Biarritz, France, 2003) |
| Biarritz by night (France, 2004) |
| AHA meeting Orlando, Florida, 2003 |
Merched A, Ko K, Tollefson K, Gotlinger K, Serhan CN, and Lawrence Chan L. Role of lipoxin A4 and inflammatory cytokines in
the 12/15-lipoxygenase mediated modulation of atherosclerosis. Oral. American Heart Association: 77th Scientific Sessions,
November 13-16, 2005 Dallas, TX, USA.
Merched A, Tollefson K and Chan L. Dynamic involvement of b2 integrins in the initiation and progression of atherosclerosis in
the LDLR knockout mouse model. Poster. American Heart Association: 77th Scientific Sessions, November 13-16, 2005
Dallas, TX, USA.
Merched A, Tollefson K, Chan L The dynamic involvement of b2 integrins in the initiation and the progression of atherosclerosis
in the LDLR knockout mouse model. Poster. 2eme Congrès Annuel NSFA - June 9-11, 2005, Biarritz, France.
Merched A, Tollefson K, Chan L. Absence of p21Waf1/Cip1/Sdi1 Modulates Macrophage Differentiation and Inflammatory
Response and Protects Against Atherosclerosis. Oral. American Heart Association: 76nd Scientific Sessions, November 7-10,
2004, New Orleans, LA, USA. Merched A and Chan L. Role of p21 (waf1) in the development of atherosclerotic lesions. Oral.
1er Congrès Annuel NSFA - 10-12 juin 2004, Biarritz , France.
Ko KWS, Merched AJ, Chan L. Macrophage-Specific Transgenic Overexpression of 15-Lipoxygenase Attenuates
Atherosclerosis in ApoE-Deficient Mice. Poster. 5th Annual Conference on Arteriosclerosis Thrombosis and Vascular Biology
Meeting May 6-8, 2004, San Francisco, CA, USA.
Merched A, Williams L and Chan L. p21 deficiency protects against atherosclerosis in apolipoprotein E knockout mice. Poster.
American Heart Association: 76th Scientific Sessions, November 2003, Orlando, FL, USA.
Kazuhiro O, Nomura S, Merched A, Pastore L, Beaudet A, Chan L. In-Vivo LDL Receptor Gene Therapy Is Highly effective in
Reversing Hypercholesterolemia in a Mouse Model of Familial Hypercholesterolemia. Poster. The 5th Annual Meeting of the
American Society of Gene Therapy. June 4-8, 2003 in Washington, DC USA.
Oka K, L. Belalcazar M, Merched A, Pastore L, Beaudet A, Chan L. Long-Term Stable Expression of Human Apolipoprotein A-I
Mediated by Helper-Dependent Adenovirus Gene Transfer Inhibits Atherosclerosis Progression and Remodels Atherosclerotic
Plaques in a Mouse Model of Familial Hypercholesterolemia. Oral. The 5th Annual Meeting of the American Society of Gene
Therapy. June 5-9, 2002, Boston, MA USA.
Merched A, Williams L and Chan L. Macrophage-specific p53 expression plays a crucial role in atherosclerosis development.
Poster. Department of Medicine Annual Research Symposium April 4, 2002, BCM Houston, TX, USA.
Nomura N, Oka K, Merched A, Pastore P, Beaudet A, Chan L. Long-Term Reversal of Hypercholesterolemia by a Single
Injection of a Helper-Dependent Adenovirus Expressing LDL Receptor Markedly Inhibits Aortic Atherosclerosis Progression in a
Mouse Model of Familial Hypercholesterolemia. Oral. American Heart Association: 74th Scientific Sessions, November 2001,
New Orleans, LO, USA.
Belalcazar M, Merched A, Carr B, Antanova E, Chen K-H, Oka K, Lucio P, Beaudet A, Chan L. Somatic Gene Therapy for Long-
Term Stable Correction of Genetic HDL Deficiency and Atherosclerotic Disease in Mice Using a Novel Nontoxic Adenoviral
Human ApoA-I Vector. Oral. American Heart Association: 73d Scientific Sessions, November 2000, New Orleans, LO, USA.
Pastore L., Oka K., Belalcazar M., Kim I.-H., Merched A., Cela R., Lee B., Beaudet A.L., Chan L.. Helper-dependent adenoviral
vectors for gene therapy of atherosclerosis. Oral. The American Society of Human Genetics Fiftieth Annual Meeting October
2000, Philadelphia PA USA.
Dergunov A.D., E. A. Smirnova, A. Merched, S. Visvikis, G. Siest Binding of triglyceride-rich lipoproteins to the LDL receptor in
hypertriglyceridemia: role of apolipoprotein E. Poster. High Density Lipoproteins And Atherosclerosis IAS Satellite Symposium,
July 1-3, 2000, Helsinki, Finland.
Chan L, K Oka, M Belalcazar, I-H Kim, A. Merched, K-H Chen, L Pastore, B Lee, A Beaudet. Novel Approaches to the Treatment
of Dyslipidemia by Liver-directed Gene. Oral. The Third Annual Meeting of the American Society of Gene Therapy, May 31 - June
4, 2000 Denver, Colorado, USA.
More communications
Oka K, Kim I-H, Merched A, Pastore L, Beaudet A, Chan L. Long-Term Expression of VLDL Receptor by a Helper-Dependent
Adenoviral Vector Reduces Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia. Oral. American Heart
Association: 72nd Scientific Sessions, 8 Novembre 1999, Atlanta, GA, USA.
Guevara NV, Merched A, Kim HS, Antonova EI, Chan L. New insights into the role of p53 in atherosclerosis. Oral. II
Minicolloqium Biologie Perspective, 22-23 March 1999, Nancy, France.
Terrisse L, Marcoux-Legault K, Merched A, Sirois J, Poirier J, Siest G, Milne R, Rassart E. Niveaux élevés d'apolipoprotéine D
dans le liquide céphalo-rachidien et dans l'hippocampe de patients atteints de la maladie d'Alzheimer. Génétique Humaine au
Québec May 21, 1998, Quebec, Canada.
Merched A, Xia Y, Papadopoulou A, Siest G and Visvikis S. Apolipoprotein AIV codon 360 mutation increases with aging and is
not associated with Alzheimer’s disease. Poster. Human Genomics. The basis of the Medicine of Tomorrow, 15-18 March,
1998, Singapour.
Jeandel C, Blain H, Merched A, Visvikis S, and Siest G. La concentration dans le LCR de l’apolipoprotéine E augmentée avec l’
avancée en âge. IVème Réunion Francophones sur la Maladie d’Alzheimer et les Syndromes Apparentées. Poster. 2-4 octobre
1997, Marseille, France.
Jeandel C, Blain H, Merched A, Visvikis S, and Siest G. Concentration dans le LCR de l’apolipoprotéine E dans le maladie d’
Alzheimer. IVème Réunion Francophones sur la Maladie d’Alzheimer et les Syndromes Apparentées. Oral. 2-4 octobre 1997,
Marseille, France.
Merched A, L. Terrisse, P. Bertrand, J. Poirier, S. Visvikis, G. Siest, R. Milne, E. Rassart Les apolipoprotéines D et E dans le
système nerveux central des patients Alzheimeriens. IVème Réunion Francophones sur la Maladie d’Alzheimer et les
Syndromes Apparentées. Poster. 2-4 octobre 1997, Marseille, France.
Merched A, S. Visvikis, J.-M. Serot, L. Terrisse, E. Rassart, G. Siest. Génétique de l’apolipoprotéine E et Association avec la
transthyrétine, l’apolipoproteine D et l’actine dans la maladie d’Alzheimer. IVème Réunion Francophones sur la Maladie d’
Alzheimer et les Syndromes Apparentées. Oral. 2-4 octobre 1997, Marseille, France.
Merched A, Blain U, Visvikis S, Jeandel C and Siest G. Le vieillissement et la maladie d’Alzheimer affectent la concentration de l’
apolipoprotéine E dans le liquide céphalorachidien. Oral. IIIème Réunion de la Société de Biologie du Vieillissement. 20 juin
1997, Paris, France.
Merched A, Visvikis S, Blain U, Jeandel C and Siest G Apolipoprotein E in cerebrospinal fluid increases with aging, Alzheimer’s
disease and some neurodegenerative pathologies. Poster. 68th Meeting of the European Atherosclerosis Society. 8-10 mai
1997, Brugge, Belgium.
the 12/15-lipoxygenase mediated modulation of atherosclerosis. Oral. American Heart Association: 77th Scientific Sessions,
November 13-16, 2005 Dallas, TX, USA.
Merched A, Tollefson K and Chan L. Dynamic involvement of b2 integrins in the initiation and progression of atherosclerosis in
the LDLR knockout mouse model. Poster. American Heart Association: 77th Scientific Sessions, November 13-16, 2005
Dallas, TX, USA.
Merched A, Tollefson K, Chan L The dynamic involvement of b2 integrins in the initiation and the progression of atherosclerosis
in the LDLR knockout mouse model. Poster. 2eme Congrès Annuel NSFA - June 9-11, 2005, Biarritz, France.
Merched A, Tollefson K, Chan L. Absence of p21Waf1/Cip1/Sdi1 Modulates Macrophage Differentiation and Inflammatory
Response and Protects Against Atherosclerosis. Oral. American Heart Association: 76nd Scientific Sessions, November 7-10,
2004, New Orleans, LA, USA. Merched A and Chan L. Role of p21 (waf1) in the development of atherosclerotic lesions. Oral.
1er Congrès Annuel NSFA - 10-12 juin 2004, Biarritz , France.
Ko KWS, Merched AJ, Chan L. Macrophage-Specific Transgenic Overexpression of 15-Lipoxygenase Attenuates
Atherosclerosis in ApoE-Deficient Mice. Poster. 5th Annual Conference on Arteriosclerosis Thrombosis and Vascular Biology
Meeting May 6-8, 2004, San Francisco, CA, USA.
Merched A, Williams L and Chan L. p21 deficiency protects against atherosclerosis in apolipoprotein E knockout mice. Poster.
American Heart Association: 76th Scientific Sessions, November 2003, Orlando, FL, USA.
Kazuhiro O, Nomura S, Merched A, Pastore L, Beaudet A, Chan L. In-Vivo LDL Receptor Gene Therapy Is Highly effective in
Reversing Hypercholesterolemia in a Mouse Model of Familial Hypercholesterolemia. Poster. The 5th Annual Meeting of the
American Society of Gene Therapy. June 4-8, 2003 in Washington, DC USA.
Oka K, L. Belalcazar M, Merched A, Pastore L, Beaudet A, Chan L. Long-Term Stable Expression of Human Apolipoprotein A-I
Mediated by Helper-Dependent Adenovirus Gene Transfer Inhibits Atherosclerosis Progression and Remodels Atherosclerotic
Plaques in a Mouse Model of Familial Hypercholesterolemia. Oral. The 5th Annual Meeting of the American Society of Gene
Therapy. June 5-9, 2002, Boston, MA USA.
Merched A, Williams L and Chan L. Macrophage-specific p53 expression plays a crucial role in atherosclerosis development.
Poster. Department of Medicine Annual Research Symposium April 4, 2002, BCM Houston, TX, USA.
Nomura N, Oka K, Merched A, Pastore P, Beaudet A, Chan L. Long-Term Reversal of Hypercholesterolemia by a Single
Injection of a Helper-Dependent Adenovirus Expressing LDL Receptor Markedly Inhibits Aortic Atherosclerosis Progression in a
Mouse Model of Familial Hypercholesterolemia. Oral. American Heart Association: 74th Scientific Sessions, November 2001,
New Orleans, LO, USA.
Belalcazar M, Merched A, Carr B, Antanova E, Chen K-H, Oka K, Lucio P, Beaudet A, Chan L. Somatic Gene Therapy for Long-
Term Stable Correction of Genetic HDL Deficiency and Atherosclerotic Disease in Mice Using a Novel Nontoxic Adenoviral
Human ApoA-I Vector. Oral. American Heart Association: 73d Scientific Sessions, November 2000, New Orleans, LO, USA.
Pastore L., Oka K., Belalcazar M., Kim I.-H., Merched A., Cela R., Lee B., Beaudet A.L., Chan L.. Helper-dependent adenoviral
vectors for gene therapy of atherosclerosis. Oral. The American Society of Human Genetics Fiftieth Annual Meeting October
2000, Philadelphia PA USA.
Dergunov A.D., E. A. Smirnova, A. Merched, S. Visvikis, G. Siest Binding of triglyceride-rich lipoproteins to the LDL receptor in
hypertriglyceridemia: role of apolipoprotein E. Poster. High Density Lipoproteins And Atherosclerosis IAS Satellite Symposium,
July 1-3, 2000, Helsinki, Finland.
Chan L, K Oka, M Belalcazar, I-H Kim, A. Merched, K-H Chen, L Pastore, B Lee, A Beaudet. Novel Approaches to the Treatment
of Dyslipidemia by Liver-directed Gene. Oral. The Third Annual Meeting of the American Society of Gene Therapy, May 31 - June
4, 2000 Denver, Colorado, USA.
More communications
Oka K, Kim I-H, Merched A, Pastore L, Beaudet A, Chan L. Long-Term Expression of VLDL Receptor by a Helper-Dependent
Adenoviral Vector Reduces Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia. Oral. American Heart
Association: 72nd Scientific Sessions, 8 Novembre 1999, Atlanta, GA, USA.
Guevara NV, Merched A, Kim HS, Antonova EI, Chan L. New insights into the role of p53 in atherosclerosis. Oral. II
Minicolloqium Biologie Perspective, 22-23 March 1999, Nancy, France.
Terrisse L, Marcoux-Legault K, Merched A, Sirois J, Poirier J, Siest G, Milne R, Rassart E. Niveaux élevés d'apolipoprotéine D
dans le liquide céphalo-rachidien et dans l'hippocampe de patients atteints de la maladie d'Alzheimer. Génétique Humaine au
Québec May 21, 1998, Quebec, Canada.
Merched A, Xia Y, Papadopoulou A, Siest G and Visvikis S. Apolipoprotein AIV codon 360 mutation increases with aging and is
not associated with Alzheimer’s disease. Poster. Human Genomics. The basis of the Medicine of Tomorrow, 15-18 March,
1998, Singapour.
Jeandel C, Blain H, Merched A, Visvikis S, and Siest G. La concentration dans le LCR de l’apolipoprotéine E augmentée avec l’
avancée en âge. IVème Réunion Francophones sur la Maladie d’Alzheimer et les Syndromes Apparentées. Poster. 2-4 octobre
1997, Marseille, France.
Jeandel C, Blain H, Merched A, Visvikis S, and Siest G. Concentration dans le LCR de l’apolipoprotéine E dans le maladie d’
Alzheimer. IVème Réunion Francophones sur la Maladie d’Alzheimer et les Syndromes Apparentées. Oral. 2-4 octobre 1997,
Marseille, France.
Merched A, L. Terrisse, P. Bertrand, J. Poirier, S. Visvikis, G. Siest, R. Milne, E. Rassart Les apolipoprotéines D et E dans le
système nerveux central des patients Alzheimeriens. IVème Réunion Francophones sur la Maladie d’Alzheimer et les
Syndromes Apparentées. Poster. 2-4 octobre 1997, Marseille, France.
Merched A, S. Visvikis, J.-M. Serot, L. Terrisse, E. Rassart, G. Siest. Génétique de l’apolipoprotéine E et Association avec la
transthyrétine, l’apolipoproteine D et l’actine dans la maladie d’Alzheimer. IVème Réunion Francophones sur la Maladie d’
Alzheimer et les Syndromes Apparentées. Oral. 2-4 octobre 1997, Marseille, France.
Merched A, Blain U, Visvikis S, Jeandel C and Siest G. Le vieillissement et la maladie d’Alzheimer affectent la concentration de l’
apolipoprotéine E dans le liquide céphalorachidien. Oral. IIIème Réunion de la Société de Biologie du Vieillissement. 20 juin
1997, Paris, France.
Merched A, Visvikis S, Blain U, Jeandel C and Siest G Apolipoprotein E in cerebrospinal fluid increases with aging, Alzheimer’s
disease and some neurodegenerative pathologies. Poster. 68th Meeting of the European Atherosclerosis Society. 8-10 mai
1997, Brugge, Belgium.
| Dr. Aksam J. Merched's Scientific Communications |
 |  |  |
| BIT's 1st Annual International Congress of Cardiology. December 5-7, 2009 Shanghai, China |